Risk factors

Certain factors may increase your risk of pyoderma gangrenosum, including:

• Your age and sex. The condition can affect anyone at any age, though it's more common between 20 and 50 years of age.
• Having inflammatory bowel disease. People with a digestive tract disease such as ulcerative colitis or Crohn's disease are at increased risk of pyoderma gangrenosum.
• Having arthritis. People with rheumatoid arthritis are at increased risk of pyoderma gangrenosum.
• Having a blood disorder. People with acute myelogenous leukemia, myelodysplasia or a myeloproliferative disorder are at increased risk of pyoderma gangrenosum.